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The longitudinal lung function data and their determinants

African and European perspectives

Date

21 April, 2026

Date

17:00 - 18:00 CEST

Overview

Lung function trajectories across the lifespan are powerful predictors of future respiratory and cardiovascular health. However, most longitudinal data and established reference equations are derived from high-income, predominantly European populations, limiting their applicability to low- and middle-income settings, particularly in Africa.

There is a critical need to understand how environmental exposures (indoor/outdoor pollution, biomass fuel), early-life infections (TB, HIV, pneumonia), socioeconomic determinants, and genetic diversity shape lung function growth and decline in African populations.

This webinar addresses this gap by bringing together experts from both continents to share data, compare findings, and discuss the implications for clinical practice and policy. It is essential for clinicians and researchers seeking to provide equitable, evidence-based respiratory care in diverse global contexts.

Key Topics

Patterns of lung function growth from childhood to adulthood: Comparing South African and European cohort data.

Key determinants of lung function trajectories: Environmental exposures (air pollution, tobacco, biomass), socioeconomic status, and nutrition.

Impact of early-life respiratory infections (TB, pneumonia, HIV) on lung function in African versus European settings.

Genetic and epigenetic influences on lung function development and decline across diverse populations.

Implications of observed disparities for clinical practice, reference value interpretation, and public health policy.

Learning Outcomes

Following this webinar, participants will be able to:

Compare and contrast patterns of lung function growth and decline observed in South African and European populations.

Identify key environmental, genetic, socioeconomic, and early-life determinants that influence lung function trajectories in both settings.

Review how differences in healthcare access, air pollution exposure, infectious diseases, and lifestyle factors contribute to regional disparities in respiratory outcomes.

Evaluate the implications of longitudinal lung function findings for public health policy, clinical practice, and future respiratory research in South Africa and Europe.

Webinar Faculty

Chairs

Prof. Refiloe Masekela

Durban, South Africa

Prof. Olena Gruzieva

Stockholm, Sweden

Speakers

Prof. Diane Gray

Cape Town, South Africa

Prof. Erik Melén

Stockholm, Sweden

CME & CPD Credit

An application for accreditation of this webinar has been made to the European Board for Accreditation in Pneumology (EBAP) and South African Medical Association for 1 CME & CPD credit per 1-hour attendance.

If accredited, the credit will be granted upon attendance of at least 60 minutes during the live webinar only.

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